| Item Type | Name |
|
Concept
|
Acetates
|
|
Concept
|
Dependovirus
|
|
Concept
|
Adenocarcinoma
|
|
Concept
|
Adenoviridae
|
|
Concept
|
Adrenalectomy
|
|
Concept
|
Age Factors
|
|
Concept
|
Acclimatization
|
|
Concept
|
Acetylation
|
|
Concept
|
Addison Disease
|
|
Concept
|
Adenoma, Chromophobe
|
|
Concept
|
Antigens, Neoplasm
|
|
Concept
|
Amyloidosis
|
|
Concept
|
Antibodies, Neoplasm
|
|
Concept
|
Apoenzymes
|
|
Concept
|
Adrenal Gland Neoplasms
|
|
Concept
|
Alkaline Phosphatase
|
|
Concept
|
Arrhythmias, Cardiac
|
|
Concept
|
Haplorhini
|
|
Concept
|
Adaptation, Physiological
|
|
Concept
|
Adenocarcinoma, Papillary
|
|
Concept
|
Adenoids
|
|
Concept
|
Adenylyl Cyclases
|
|
Concept
|
Adenoma
|
|
Concept
|
Cyclic AMP
|
|
Concept
|
Acromegaly
|
|
Concept
|
Benz(a)Anthracenes
|
|
Concept
|
alpha 1-Antitrypsin
|
|
Concept
|
Amenorrhea
|
|
Concept
|
Bile Acids and Salts
|
|
Concept
|
Binding Sites, Antibody
|
|
Concept
|
Brain Damage, Chronic
|
|
Concept
|
Alleles
|
|
Concept
|
Amino Acid Sequence
|
|
Concept
|
Administration, Intranasal
|
|
Concept
|
Adrenocorticotropic Hormone
|
|
Concept
|
Agranulocytosis
|
|
Concept
|
Albuminuria
|
|
Concept
|
Blood Protein Disorders
|
|
Concept
|
Blood Proteins
|
|
Concept
|
Body Fluids
|
|
Concept
|
Antigens
|
|
Concept
|
Antineoplastic Agents
|
|
Concept
|
Carcinoma, Papillary
|
|
Concept
|
Central Nervous System Diseases
|
|
Concept
|
Cerebral Cortex
|
|
Concept
|
Charcoal
|
|
Concept
|
Chiari-Frommel Syndrome
|
|
Concept
|
Aneuploidy
|
|
Concept
|
Animals
|
|
Concept
|
Animals, Newborn
|
|
Concept
|
Antineoplastic Combined Chemotherapy Protocols
|
|
Concept
|
Anura
|
|
Concept
|
Carbohydrate Conformation
|
|
Concept
|
Carcinoma
|
|
Concept
|
Androgens
|
|
Concept
|
Anilino Naphthalenesulfonates
|
|
Concept
|
Chloromercuribenzoates
|
|
Concept
|
Antioxidants
|
|
Concept
|
Analysis of Variance
|
|
Concept
|
Anthropometry
|
|
Concept
|
Antibodies, Monoclonal
|
|
Concept
|
Arginine
|
|
Concept
|
Arousal
|
|
Concept
|
B-Lymphocytes
|
|
Concept
|
Basal Metabolism
|
|
Concept
|
Base Sequence
|
|
Concept
|
Benzamides
|
|
Concept
|
Celiac Disease
|
|
Concept
|
Cell Movement
|
|
Concept
|
Cell Nucleus
|
|
Concept
|
Diabetes Mellitus, Experimental
|
|
Concept
|
Aspartic Acid
|
|
Concept
|
Autoantigens
|
|
Concept
|
Azores
|
|
Concept
|
Bangladesh
|
|
Concept
|
DNA Damage
|
|
Concept
|
Blood Urea Nitrogen
|
|
Concept
|
Blood Vessels
|
|
Concept
|
Body Height
|
|
Concept
|
Bone Neoplasms
|
|
Concept
|
Autoradiography
|
|
Concept
|
Basement Membrane
|
|
Concept
|
Athetosis
|
|
Concept
|
Autoantibodies
|
|
Concept
|
Binding Sites
|
|
Concept
|
Biological Clocks
|
|
Concept
|
Birth Weight
|
|
Concept
|
Blood Glucose
|
|
Concept
|
Body Temperature Regulation
|
|
Concept
|
Dihydroxyphenylalanine
|
|
Concept
|
beta-Endorphin
|
|
Concept
|
Biopsy, Needle
|
|
Concept
|
Bleomycin
|
|
Concept
|
beta-Galactosidase
|
|
Concept
|
Biopsy
|
|
Concept
|
Blood
|
|
Concept
|
Blood Protein Electrophoresis
|
|
Concept
|
Body Weight
|
|
Concept
|
Butyrates
|
|
Concept
|
Calcification, Physiologic
|
|
Concept
|
Cattle
|
|
Concept
|
Cell Membrane
|
|
Concept
|
Bromocriptine
|
|
Concept
|
Chromatography, Gel
|
|
Concept
|
Chromosomes, Human, Pair 15
|
|
Concept
|
Chromosomes, Human, Pair 3
|
|
Concept
|
Clone Cells
|
|
Concept
|
Complement System Proteins
|
|
Concept
|
Cell Transformation, Viral
|
|
Concept
|
Cell-Free System
|
|
Concept
|
Cerebellum
|
|
Concept
|
Chromosomes, Human, 6-12 and X
|
|
Concept
|
Colonic Neoplasms
|
|
Concept
|
Cell Transformation, Neoplastic
|
|
Concept
|
Chicago
|
|
Concept
|
Child Development
|
|
Concept
|
Chromosome Deletion
|
|
Concept
|
Codon
|
|
Concept
|
Blood-Brain Barrier
|
|
Concept
|
Genes, Synthetic
|
|
Concept
|
Cardiotonic Agents
|
|
Concept
|
Glucose-6-Phosphatase
|
|
Concept
|
Glutathione Transferase
|
|
Concept
|
Ovarian Follicle
|
|
Concept
|
Growth Disorders
|
|
Concept
|
Guinea Pigs
|
|
Concept
|
Concanavalin A
|
|
Concept
|
Corticotropin-Releasing Hormone
|
|
Concept
|
Cortisone
|
|
Concept
|
Cricetulus
|
|
Concept
|
Computers
|
|
Concept
|
Cholesterol
|
|
Concept
|
Chorea
|
|
Concept
|
Chromosomal Proteins, Non-Histone
|
|
Concept
|
Circadian Rhythm
|
|
Concept
|
Hearing Loss, Sensorineural
|
|
Concept
|
Hematocrit
|
|
Concept
|
Cytosine Nucleotides
|
|
Concept
|
Cytosol
|
|
Concept
|
Hormones
|
|
Concept
|
Culture Media
|
|
Concept
|
Darkness
|
|
Concept
|
Hypothermia
|
|
Concept
|
Ileum
|
|
Concept
|
Immunogenetics
|
|
Concept
|
Diagnostic Errors
|
|
Concept
|
DNA Transposable Elements
|
|
Concept
|
DNA-Binding Proteins
|
|
Concept
|
DNA, Mitochondrial
|
|
Concept
|
Cushing Syndrome
|
|
Concept
|
Cycloheximide
|
|
Concept
|
Cysteine Endopeptidases
|
|
Concept
|
Cystine
|
|
Concept
|
Cytochrome c Group
|
|
Concept
|
Cytoplasm
|
|
Concept
|
Defective Viruses
|
|
Concept
|
Dexamethasone
|
|
Concept
|
Diet
|
|
Concept
|
Immunoglobulin Fab Fragments
|
|
Concept
|
Injections, Intraperitoneal
|
|
Concept
|
Inositol Phosphates
|
|
Concept
|
Insulin
|
|
Concept
|
Congenital Hypothyroidism
|
|
Concept
|
Cystinosis
|
|
Concept
|
Dithiothreitol
|
|
Concept
|
DNA, Bacterial
|
|
Concept
|
Dose-Response Relationship, Radiation
|
|
Concept
|
Catecholamines
|
|
Concept
|
Dogs
|
|
Concept
|
Dosage Compensation, Genetic
|
|
Concept
|
Fetal Resorption
|
|
Concept
|
Ghana
|
|
Concept
|
Glucocorticoids
|
|
Concept
|
Chorionic Gonadotropin
|
|
Concept
|
Hybridomas
|
|
Concept
|
Endoplasmic Reticulum
|
|
Concept
|
Endorphins
|
|
Concept
|
Enzyme Inhibitors
|
|
Concept
|
Estradiol
|
|
Concept
|
Hypothalamo-Hypophyseal System
|
|
Concept
|
Diiodothyronines
|
|
Concept
|
Diiodotyrosine
|
|
Concept
|
Chromones
|
|
Concept
|
Chronic Disease
|
|
Concept
|
Exons
|
|
Concept
|
Mass Screening
|
|
Concept
|
Extracellular Space
|
|
Concept
|
Congresses as Topic
|
|
Concept
|
Dextrans
|
|
Concept
|
Deafness
|
|
Concept
|
Dimethylformamide
|
|
Concept
|
Double-Blind Method
|
|
Concept
|
Diseases in Twins
|
|
Concept
|
Eating
|
|
Concept
|
Follicle Stimulating Hormone
|
|
Concept
|
Fatty Liver
|
|
Concept
|
Ferritins
|
|
Concept
|
Infant, Newborn
|
|
Concept
|
Infant, Premature
|
|
Concept
|
Introns
|
|
Concept
|
Mice, Inbred C3H
|
|
Concept
|
Fluorescence
|
|
Concept
|
gamma-Globulins
|
|
Concept
|
Multienzyme Complexes
|
|
Concept
|
Muscle Hypotonia
|
|
Concept
|
Genes, Dominant
|
|
Concept
|
Glucosamine
|
|
Concept
|
Genes
|
|
Concept
|
Fasting
|
|
Concept
|
Fatty Acids
|
|
Concept
|
Fatty Acids, Unsaturated
|
|
Concept
|
Fibronectins
|
|
Concept
|
Neoplasms, Radiation-Induced
|
|
Concept
|
Terminology as Topic
|
|
Concept
|
Israel
|
|
Concept
|
Karyotyping
|
|
Concept
|
Genes, Recessive
|
|
Concept
|
Obesity
|
|
Concept
|
Oncogenes
|
|
Concept
|
Glucose Oxidase
|
|
Concept
|
Histocytochemistry
|
|
Concept
|
Heart
|
|
Concept
|
Electroencephalography
|
|
Concept
|
Electromyography
|
|
Concept
|
Embryo, Mammalian
|
|
Concept
|
DNA, Viral
|
|
Concept
|
Dose-Response Relationship, Drug
|
|
Concept
|
Dwarfism, Pituitary
|
|
Concept
|
Hungary
|
|
Concept
|
Hydrogen Peroxide
|
|
Concept
|
Immune Sera
|
|
Concept
|
beta-Lipotropin
|
|
Concept
|
Liver Neoplasms
|
|
Concept
|
Long-Acting Thyroid Stimulator
|
|
Concept
|
Indium
|
|
Concept
|
Insulin-Like Growth Factor I
|
|
Concept
|
Perchlorates
|
|
Concept
|
Energy Metabolism
|
|
Concept
|
Enzyme-Linked Immunosorbent Assay
|
|
Concept
|
Eosinophilia
|
|
Concept
|
Herpesvirus 4, Human
|
|
Concept
|
Escherichia coli
|
|
Concept
|
Hydrocortisone
|
|
Concept
|
Feedback
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Fluorometry
|
|
Concept
|
Immunosorbent Techniques
|
|
Concept
|
Immunodiffusion
|
|
Concept
|
Gene Amplification
|
|
Concept
|
Multigene Family
|
|
Concept
|
Gigantism
|
|
Concept
|
Goats
|
|
Concept
|
Goiter, Endemic
|
|
Concept
|
Lactation Disorders
|
|
Concept
|
Light
|
|
Concept
|
Heme
|
|
Concept
|
Macrophages
|
|
Concept
|
Iodides
|
|
Concept
|
Isoelectric Point
|
|
Concept
|
Metanephrine
|
|
Concept
|
Carcinoma, Hepatocellular
|
|
Concept
|
Maternal Age
|
|
Concept
|
Membrane Proteins
|
|
Concept
|
Leukocytes
|
|
Concept
|
Leydig Cells
|
|
Concept
|
Gonadotropin-Releasing Hormone
|
|
Concept
|
Hyperplasia
|
|
Concept
|
Mice, Inbred Strains
|
|
Concept
|
Microfilament Proteins
|
|
Concept
|
Models, Molecular
|
|
Concept
|
Mosaicism
|
|
Concept
|
Movement Disorders
|
|
Concept
|
Phenolsulfonphthalein
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Mitosis
|
|
Concept
|
Models, Genetic
|
|
Concept
|
Nerve Compression Syndromes
|
|
Concept
|
Nerve Tissue Proteins
|
|
Concept
|
Mannose
|
|
Concept
|
Estrogens
|
|
Concept
|
Ethchlorvynol
|
|
Concept
|
Protein Denaturation
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Organ Size
|
|
Concept
|
Molecular Sequence Data
|
|
Concept
|
Nelson Syndrome
|
|
Concept
|
Glycogen
|
|
Concept
|
Glycolysis
|
|
Concept
|
Goiter, Nodular
|
|
Concept
|
Graves Disease
|
|
Concept
|
Intellectual Disability
|
|
Concept
|
Mice, Inbred BALB C
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Random Allocation
|
|
Concept
|
Molecular Biology
|
|
Concept
|
Muscular Atrophy
|
|
Concept
|
Cricetinae
|
|
Concept
|
Hot Temperature
|
|
Concept
|
HeLa Cells
|
|
Concept
|
Hepatitis
|
|
Concept
|
Paralysis
|
|
Concept
|
Iodine Isotopes
|
|
Concept
|
Isotope Labeling
|
|
Concept
|
Neck
|
|
Concept
|
Nerve Fibers, Myelinated
|
|
Concept
|
Synaptic Transmission
|
|
Concept
|
Laminin
|
|
Concept
|
Phosphatidylinositols
|
|
Concept
|
Nucleic Acid Conformation
|
|
Concept
|
Ovarian Diseases
|
|
Concept
|
Oxidation-Reduction
|
|
Concept
|
Luciferases
|
|
Concept
|
Lung Neoplasms
|
|
Concept
|
Selenium
|
|
Concept
|
Serum Albumin, Radio-Iodinated
|
|
Concept
|
Sleep Stages
|
|
Concept
|
Pheochromocytoma
|
|
Concept
|
Pituitary Gland, Anterior
|
|
Concept
|
Placental Hormones
|
|
Concept
|
Poly A
|
|
Concept
|
Polyribosomes
|
|
Concept
|
Morpholines
|
|
Concept
|
Muscle Proteins
|
|
Concept
|
Netherlands
|
|
Concept
|
Nuclear Family
|
|
Concept
|
Operon
|
|
Concept
|
Osteogenesis
|
|
Concept
|
Oxygen
|
|
Concept
|
Feeding Behavior
|
|
Concept
|
Embryonic and Fetal Development
|
|
Concept
|
Pituitary Diseases
|
|
Concept
|
Polyribonucleotides
|
|
Concept
|
Switzerland
|
|
Concept
|
Propionates
|
|
Concept
|
Prednisone
|
|
Concept
|
Pregnancy Outcome
|
|
Concept
|
Thyroidectomy
|
|
Concept
|
Thyronines
|
|
Concept
|
Pituitary Gland
|
|
Concept
|
Placental Lactogen
|
|
Concept
|
Protein Binding
|
|
Concept
|
Protein Conformation
|
|
Concept
|
Protein Processing, Post-Translational
|
|
Concept
|
Proto-Oncogene Proteins
|
|
Concept
|
Quebec
|
|
Concept
|
Proteins
|
|
Concept
|
Psychomotor Performance
|
|
Concept
|
Gallium
|
|
Concept
|
Glycogen Storage Disease Type I
|
|
Concept
|
Glutens
|
|
Concept
|
Hypophysectomy
|
|
Concept
|
Hypopituitarism
|
|
Concept
|
Immunoglobulin G
|
|
Concept
|
Immunoelectrophoresis
|
|
Concept
|
Immunoenzyme Techniques
|
|
Concept
|
Receptors, Thyrotropin
|
|
Concept
|
Regression Analysis
|
|
Concept
|
Rabbits
|
|
Concept
|
Rats, Zucker
|
|
Concept
|
Receptors, Cell Surface
|
|
Concept
|
Receptors, LH
|
|
Concept
|
Repressor Proteins
|
|
Concept
|
Pronase
|
|
Concept
|
Protein Kinases
|
|
Concept
|
Psychomotor Disorders
|
|
Concept
|
Quadriplegia
|
|
Concept
|
Sequence Homology, Nucleic Acid
|
|
Concept
|
Receptors, LDL
|
|
Concept
|
Xenopus
|
|
Concept
|
Insulin Resistance
|
|
Concept
|
Intestinal Absorption
|
|
Concept
|
Intestinal Mucosa
|
|
Concept
|
Intestine, Small
|
|
Concept
|
Iodine
|
|
Concept
|
Iopanoic Acid
|
|
Concept
|
Shrews
|
|
Concept
|
Sleep Deprivation
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Rats, Inbred Lew
|
|
Concept
|
Reagent Kits, Diagnostic
|
|
Concept
|
Regulatory Sequences, Nucleic Acid
|
|
Concept
|
Polymorphism, Restriction Fragment Length
|
|
Concept
|
Sodium
|
|
Concept
|
Seasons
|
|
Concept
|
Sex Chromosomes
|
|
Concept
|
Japan
|
|
Concept
|
DNA-Directed RNA Polymerases
|
|
Concept
|
Sensitivity and Specificity
|
|
Concept
|
Sleep, REM
|
|
Concept
|
Spain
|
|
Concept
|
Swine
|
|
Concept
|
Texas
|
|
Concept
|
Thyroxine-Binding Proteins
|
|
Concept
|
Sheep
|
|
Concept
|
Sulfites
|
|
Concept
|
Sympathetic Nervous System
|
|
Concept
|
Humans
|
|
Concept
|
Immunization
|
|
Concept
|
Incidence
|
|
Concept
|
Cluster Analysis
|
|
Concept
|
Transcription, Genetic
|
|
Concept
|
Protein Biosynthesis
|
|
Concept
|
Tretinoin
|
|
Concept
|
Thailand
|
|
Concept
|
Sulfur Radioisotopes
|
|
Concept
|
Synapses
|
|
Concept
|
Statistics as Topic
|
|
Concept
|
Triiodothyronine
|
|
Concept
|
Tritium
|
|
Concept
|
Trophoblastic Neoplasms
|
|
Concept
|
CHO Cells
|
|
Concept
|
United States
|
|
Concept
|
Syndrome
|
|
Concept
|
Sequence Homology, Amino Acid
|
|
Concept
|
Tamoxifen
|
|
Concept
|
Xenopus laevis
|
|
Concept
|
Iodine Radioisotopes
|
|
Concept
|
Kidney Failure, Chronic
|
|
Concept
|
Receptors, Thyrotropin-Releasing Hormone
|
|
Concept
|
Germ-Line Mutation
|
|
Concept
|
Deoxyribonuclease EcoRI
|
|
Concept
|
Multicenter Studies as Topic
|
|
Concept
|
Oligonucleotide Probes
|
|
Concept
|
17-Ketosteroids
|
|
Concept
|
Liver Glycogen
|
|
Concept
|
Lysosomes
|
|
Concept
|
Antithyroid Agents
|
|
Concept
|
Thyrotropin
|
|
Concept
|
Thyroxine
|
|
Concept
|
Hematopoietic Stem Cell Transplantation
|
|
Concept
|
Codon, Terminator
|
|
Concept
|
Weight Loss
|
|
Concept
|
Trans-Activators
|
|
Concept
|
Neonatal Screening
|
|
Concept
|
Risk Assessment
|
|
Concept
|
Radiopharmaceuticals
|
|
Concept
|
Chromosome Segregation
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Trichloroacetic Acid
|
|
Concept
|
Tumor Cells, Cultured
|
|
Concept
|
Turner Syndrome
|
|
Concept
|
Tyrosine
|
|
Concept
|
Protein Subunits
|
|
Concept
|
RNA Splice Sites
|
|
Concept
|
Models, Animal
|
|
Concept
|
Vitamins
|
|
Concept
|
Wakefulness
|
|
Concept
|
Electrophoretic Mobility Shift Assay
|
|
Concept
|
Deoxyribonucleases, Type II Site-Specific
|
|
Concept
|
Prevalence
|
|
Concept
|
Mutagenesis
|
|
Concept
|
DNA, Antisense
|
|
Concept
|
LDL-Receptor Related Protein-Associated Protein
|
|
Concept
|
Metabolic Clearance Rate
|
|
Concept
|
Methimazole
|
|
Concept
|
Mice, Inbred DBA
|
|
Concept
|
Mice, Inbred ICR
|
|
Concept
|
Exercise
|
|
Concept
|
Microsomes
|
|
Concept
|
Molecular Probes
|
|
Concept
|
DNA Probes
|
|
Concept
|
Weight Gain
|
|
Concept
|
Interleukin-4
|
|
Concept
|
Culture Media, Conditioned
|
|
Concept
|
Gene Expression
|
|
Concept
|
Rats, Sprague-Dawley
|
|
Concept
|
Rats, Wistar
|
|
Concept
|
Mutagenesis, Site-Directed
|
|
Concept
|
Myocardium
|
|
Concept
|
Myxedema
|
|
Concept
|
Case-Control Studies
|
|
Concept
|
In Situ Hybridization
|
|
Concept
|
Protein Structure, Tertiary
|
|
Concept
|
Receptor, IGF Type 1
|
|
Concept
|
Methionine
|
|
Concept
|
Methods
|
|
Concept
|
Methylation
|
|
Concept
|
Genes, Reporter
|
|
Concept
|
Mice, Obese
|
|
Concept
|
Microsurgery
|
|
Concept
|
Mitochondria, Liver
|
|
Concept
|
Treatment Outcome
|
|
Concept
|
Myelin Sheath
|
|
Concept
|
Cardiomyopathies
|
|
Concept
|
Neoplasm Metastasis
|
|
Concept
|
Neoplasms, Experimental
|
|
Concept
|
Oculomotor Muscles
|
|
Concept
|
Oligodeoxyribonucleotides
|
|
Concept
|
Consensus Sequence
|
|
Concept
|
RNA-Binding Proteins
|
|
Concept
|
Point Mutation
|
|
Concept
|
Nafarelin
|
|
Concept
|
Gene Deletion
|
|
Concept
|
Sequence Deletion
|
|
Concept
|
Fetal Development
|
|
Concept
|
MAP Kinase Kinase 1
|
|
Concept
|
Hepatoblastoma
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Receptors, Somatostatin
|
|
Concept
|
Thyroid Hormone Resistance Syndrome
|
|
Concept
|
DNA, Complementary
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Hyperthyroxinemia, Familial Dysalbuminemic
|
|
Concept
|
Chemokines
|
|
Concept
|
Disease Progression
|
|
Concept
|
GTP-Binding Protein alpha Subunits, Gs
|
|
Concept
|
Muscle, Skeletal
|
|
Concept
|
Founder Effect
|
|
Concept
|
Basic-Leucine Zipper Transcription Factors
|
|
Concept
|
Adenocarcinoma, Follicular
|
|
Concept
|
Th2 Cells
|
|
Concept
|
Hepatocyte Nuclear Factor 1-alpha
|
|
Concept
|
3-Iodobenzylguanidine
|
|
Concept
|
Multiple Endocrine Neoplasia Type 2a
|
|
Concept
|
Transgenes
|
|
Concept
|
Jet Lag Syndrome
|
|
Concept
|
Rats, Inbred Dahl
|
|
Concept
|
Smad1 Protein
|
|
Concept
|
Protein Transport
|
|
Concept
|
Mutation, Missense
|
|
Concept
|
Amino Acid Transport Systems, Neutral
|
|
Concept
|
Fusion Regulatory Protein 1, Light Chains
|
|
Concept
|
Embryonic Stem Cells
|
|
Concept
|
Xenopus Proteins
|
|
Concept
|
Cross-Over Studies
|
|
Concept
|
Insulin-Like Growth Factor Binding Proteins
|
|
Concept
|
Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase
|
|
Concept
|
In Situ Hybridization, Fluorescence
|
|
Concept
|
Protein Structure, Secondary
|
|
Concept
|
Protein Folding
|
|
Concept
|
Molecular Diagnostic Techniques
|
|
Concept
|
Megalencephaly
|
|
Concept
|
Primary Cell Culture
|
|
Concept
|
Receptors, G-Protein-Coupled
|
|
Concept
|
Serum
|
|
Concept
|
Iron-Binding Proteins
|
|
Concept
|
Thyroid Hormone Receptors alpha
|
|
Concept
|
Mental Retardation, X-Linked
|
|
Concept
|
Hepatocyte Nuclear Factor 1
|
|
Concept
|
Paired Box Transcription Factors
|
|
Concept
|
Hypoxia-Inducible Factor 1, alpha Subunit
|
|
Concept
|
Proteasome Endopeptidase Complex
|
|
Concept
|
Proto-Oncogene Proteins c-bcl-2
|
|
Concept
|
Clinical Laboratory Techniques
|
|
Concept
|
COS Cells
|
|
Concept
|
Microscopy, Confocal
|
|
Concept
|
Amino Acid Substitution
|
|
Concept
|
Proto-Oncogene Proteins B-raf
|
|
Concept
|
Alu Elements
|
|
Concept
|
5' Untranslated Regions
|
|
Concept
|
Response Elements
|
|
Concept
|
Congenital Disorders of Glycosylation
|
|
Concept
|
Oligonucleotide Array Sequence Analysis
|
|
Concept
|
Leptin
|
|
Concept
|
Vaccines, DNA
|
|
Concept
|
Bone Morphogenetic Proteins
|
|
Concept
|
Sirolimus
|
|
Concept
|
Databases, Genetic
|
|
Concept
|
Myopathies, Structural, Congenital
|
|
Concept
|
Polycystic Ovary Syndrome
|
|
Concept
|
Monocarboxylic Acid Transporters
|
|
Concept
|
Organic Cation Transport Proteins
|
|
Concept
|
Organic Anion Transporters, Sodium-Independent
|
|
Concept
|
Prenatal Exposure Delayed Effects
|
|
Concept
|
Animals, Genetically Modified
|
|
Concept
|
Postoperative Complications
|
|
Concept
|
Precipitin Tests
|
|
Concept
|
Prolactin
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
Pseudohypoparathyroidism
|
|
Concept
|
Psychiatric Status Rating Scales
|
|
Concept
|
Mice
|
|
Concept
|
Nuclear Receptor Coactivator 2
|
|
Concept
|
Rats, Inbred BN
|
|
Concept
|
Recombinant Proteins
|
|
Concept
|
Pyrroles
|
|
Concept
|
Radioimmunoassay
|
|
Concept
|
Rats, Inbred Strains
|
|
Concept
|
Ribonucleases
|
|
Concept
|
Ribosomal Proteins
|
|
Concept
|
Severity of Illness Index
|
|
Concept
|
Tandem Mass Spectrometry
|
|
Concept
|
Reflex, Stretch
|
|
Concept
|
Research Design
|
|
Concept
|
Respiratory Distress Syndrome, Newborn
|
|
Concept
|
RNA, Messenger
|
|
Concept
|
Sampling Studies
|
|
Concept
|
South Dakota
|
|
Concept
|
Sulfonamides
|
|
Concept
|
Congenital Hyperinsulinism
|
|
Concept
|
Testosterone
|
|
Concept
|
Thiocyanates
|
|
Concept
|
Acute Lung Injury
|
|
Concept
|
Lingual Goiter
|
|
Concept
|
Unfolded Protein Response
|
|
Concept
|
MAP Kinase Kinase Kinase 2
|
|
Concept
|
HEK293 Cells
|
|
Concept
|
Rats
|
|
Concept
|
Dried Blood Spot Testing
|
|
Concept
|
Palatine Tonsil
|
|
Concept
|
Cathepsin G
|
|
Concept
|
Kruppel-Like Transcription Factors
|
|
Concept
|
Retinoid X Receptors
|
|
Concept
|
Pituitary ACTH Hypersecretion
|
|
Concept
|
Trypsin
|
|
Concept
|
Sialic Acids
|
|
Concept
|
Sleep
|
|
Concept
|
Growth Hormone
|
|
Concept
|
Subcellular Fractions
|
|
Concept
|
MAP Kinase Kinase Kinase 1
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Temperature
|
|
Concept
|
Zebrafish
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Glycoprotein Hormones, alpha Subunit
|
|
Concept
|
Chloramphenicol O-Acetyltransferase
|
|
Concept
|
Protein Multimerization
|
|
Concept
|
PTEN Phosphohydrolase
|
|
Concept
|
NF-E2-Related Factor 2
|
|
Concept
|
Histone Acetyltransferases
|
|
Concept
|
Survival Analysis
|
|
Concept
|
Evoked Potentials, Auditory, Brain Stem
|
|
Concept
|
Thyroxine-Binding Globulin
|
|
Concept
|
Tetradecanoylphorbol Acetate
|
|
Concept
|
Thyroid Neoplasms
|
|
Concept
|
Thyrotropin-Releasing Hormone
|
|
Concept
|
Frameshift Mutation
|
|
Concept
|
Mice, 129 Strain
|
|
Concept
|
Circadian Clocks
|
|
Concept
|
Tooth
|
|
Concept
|
Phosphatidylinositol 3-Kinase
|
|
Concept
|
Turkey
|
|
Concept
|
Electrophoresis, Gel, Two-Dimensional
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
Minor Histocompatibility Antigens
|
|
Concept
|
Receptors, Corticotropin
|
|
Concept
|
Codon, Nonsense
|
|
Concept
|
Odds Ratio
|
|
Concept
|
Polymerase Chain Reaction
|
|
Concept
|
Proto-Oncogene Proteins p21(ras)
|
|
Concept
|
Genes, erbA
|
|
Concept
|
Spheroids, Cellular
|
|
Concept
|
Phlebotomy
|
|
Concept
|
GTP-Binding Proteins
|
|
Concept
|
NADPH Oxidases
|
|
Concept
|
Dimerization
|
|
Concept
|
Dietary Supplements
|
|
Concept
|
Butyric Acid
|
|
Concept
|
Antiporters
|
|
Concept
|
Nystagmus, Congenital
|
|
Concept
|
Repetitive Sequences, Amino Acid
|
|
Concept
|
Sequence Analysis, Protein
|
|
Concept
|
Gene Silencing
|
|
Concept
|
Neurotransmitter Agents
|
|
Concept
|
Homeodomain Proteins
|
|
Concept
|
Low Density Lipoprotein Receptor-Related Protein-2
|
|
Concept
|
Anion Transport Proteins
|
|
Concept
|
Immunoglobulins, Thyroid-Stimulating
|
|
Concept
|
Leukocyte Elastase
|
|
Concept
|
Ki-67 Antigen
|
|
Concept
|
Chemical and Drug Induced Liver Injury
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
Two-Hybrid System Techniques
|
|
Concept
|
Dystonic Disorders
|
|
Concept
|
MAP Kinase Signaling System
|
|
Concept
|
Protein Sorting Signals
|
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
|
Concept
|
History, 20th Century
|
|
Concept
|
Organic Anion Transporters
|
|
Concept
|
Mutant Proteins
|
|
Concept
|
Glycerol-3-Phosphate Dehydrogenase (NAD+)
|
|
Concept
|
Infusions, Intraventricular
|
|
Concept
|
Hepatocyte Nuclear Factor 1-beta
|
|
Concept
|
Neurogranin
|
|
Concept
|
Smad5 Protein
|
|
Concept
|
Transcriptome
|
|
Concept
|
Cerebrum
|
|
Concept
|
Ventilator-Induced Lung Injury
|
|
Concept
|
Metabolomics
|
|
Concept
|
Nuclear Receptor Coactivator 1
|
|
Concept
|
Siblings
|
|
Concept
|
Organogenesis
|
|
Concept
|
Ribosomal Protein S6 Kinases, 70-kDa
|
|
Concept
|
Vascular Endothelial Growth Factor A
|
|
Concept
|
Cell Line, Tumor
|
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p27
|
|
Concept
|
Forkhead Transcription Factors
|
|
Concept
|
Gene Knock-In Techniques
|
|
Concept
|
Induced Pluripotent Stem Cells
|
|
Concept
|
Th17 Cells
|
|
Concept
|
Anti-Bacterial Agents
|
|
Concept
|
Antibodies
|
|
Concept
|
Binding, Competitive
|
|
Concept
|
Bone Development
|
|
Concept
|
Calcium
|
|
Concept
|
Canada
|
|
Concept
|
Carcinoembryonic Antigen
|
|
Concept
|
Carrier Proteins
|
|
Concept
|
Cell Line
|
|
Concept
|
Cells, Cultured
|
|
Concept
|
Chromatin
|
|
Concept
|
Chromosomes
|
|
Concept
|
Clinical Trials as Topic
|
|
Concept
|
Deoxycytidine
|
|
Concept
|
Drug Eruptions
|
|
Concept
|
Diabetes Mellitus
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
DNA Restriction Enzymes
|
|
Concept
|
Doxorubicin
|
|
Concept
|
Drinking
|
|
Concept
|
Drug Screening Assays, Antitumor
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Epinephrine
|
|
Concept
|
Erythrocytes
|
|
Concept
|
Estriol
|
|
Concept
|
Estrone
|
|
Concept
|
Fetal Death
|
|
Concept
|
Follow-Up Studies
|
|
Concept
|
Genetic Counseling
|
|
Concept
|
Genetic Testing
|
|
Concept
|
Gestational Age
|
|
Concept
|
Heart Rate
|
|
Concept
|
Hemagglutination Tests
|
|
Concept
|
Horses
|
|
Concept
|
Hyperkinesis
|
|
Concept
|
Hypothalamus
|
|
Concept
|
Immunochemistry
|
|
Concept
|
Immunoglobulins
|
|
Concept
|
Iodide Peroxidase
|
|
Concept
|
Monoiodotyrosine
|
|
Concept
|
Iran
|
|
Concept
|
Jejunum
|
|
Concept
|
Luteinizing Hormone
|
|
Concept
|
Longitudinal Studies
|
|
Concept
|
Luminescent Proteins
|
|
Concept
|
Lymphocyte Activation
|
|
Concept
|
Lymphocytes
|
|
Concept
|
Lysine
|
|
Concept
|
Magnetic Resonance Imaging
|
|
Concept
|
Mice, Mutant Strains
|
|
Concept
|
Microscopy, Fluorescence
|
|
Concept
|
Models, Biological
|
|
Concept
|
Mothers
|
|
Concept
|
Neoplasm Invasiveness
|
|
Concept
|
Neoplasm Proteins
|
|
Concept
|
Niacin
|
|
Concept
|
Norepinephrine
|
|
Concept
|
Nuclear Proteins
|
|
Concept
|
Oligonucleotides
|
|
Concept
|
Pakistan
|
|
Concept
|
Patient Compliance
|
|
Concept
|
Personality Assessment
|
|
Concept
|
Pituitary Hormones, Anterior
|
|
Concept
|
Pituitary Neoplasms
|
|
Concept
|
Predictive Value of Tests
|
|
Concept
|
Prospective Studies
|
|
Concept
|
Recombinant Fusion Proteins
|
|
Concept
|
Reticulocytes
|
|
Concept
|
Retrospective Studies
|
|
Concept
|
Sex Hormone-Binding Globulin
|
|
Concept
|
Sudan
|
|
Concept
|
Tetrahydronaphthalenes
|
|
Concept
|
Thymus Gland
|
|
Concept
|
Triiodothyronine, Reverse
|
|
Concept
|
X Chromosome
|
|
Concept
|
Tumor Suppressor Protein p53
|
|
Concept
|
Cytokines
|
|
Concept
|
Mutagenesis, Insertional
|
|
Concept
|
Oligonucleotides, Antisense
|
|
Concept
|
Age of Onset
|
|
Concept
|
DNA Primers
|
|
Concept
|
Genetic Predisposition to Disease
|
|
Concept
|
Protein Isoforms
|
|
Concept
|
Polymorphism, Single Nucleotide
|
|
Concept
|
Collagen Type IV
|
|
Concept
|
Phosphofructokinase-1, Type C
|
|
Concept
|
Membrane Transport Proteins
|
|
Concept
|
Amino Acid Transport System y+
|
|
Concept
|
Amino Acid Transport System y+L
|
|
Concept
|
Symporters
|
|
Concept
|
Thyrotropin, beta Subunit
|
|
Concept
|
Chromosomes, Human, X
|
|
Concept
|
Protein Kinase Inhibitors
|
|
Concept
|
Proto-Oncogene Proteins c-akt
|
|
Concept
|
Glucose Transporter Type 4
|
|
Concept
|
Neurogenesis
|
|
Concept
|
Class III Phosphatidylinositol 3-Kinases
|
|
Academic Article
|
In vitro expression of thyroxine-binding globulin (TBG) variants. Impaired secretion of TBGPRO-227 but not TBGPRO-113.
|
|
Academic Article
|
Attention-deficit hyperactivity disorder and thyroid function.
|
|
Academic Article
|
Multiple genetic factors in the heterogeneity of thyroid hormone resistance.
|
|
Academic Article
|
Identical mutations in unrelated families with generalized resistance to thyroid hormone occur in cytosine-guanine-rich areas of the thyroid hormone receptor beta gene. Analysis of 15 families.
|
|
Academic Article
|
Thyroid function tests and characterization of thyroxine-binding globulin in the carbohydrate-deficient glycoprotein syndrome type I.
|
|
Academic Article
|
Expression of thyroid peroxidase in EBV-transformed B cell lines using adenovirus.
|
|
Academic Article
|
A mouse model of resistance to thyroid hormone produced by somatic gene transfer of a mutant thyroid hormone receptor.
|
|
Academic Article
|
Effects of aging on glucose regulation during wakefulness and sleep.
|
|
Academic Article
|
Thyroid dysfunction is not associated with alterations in serum leptin levels.
|
|
Academic Article
|
Resistance to thyrotropin and other abnormalities of the thyrotropin receptor.
|
|
Academic Article
|
Mutation in the thyroid hormone receptor (TR) beta gene (M313T) not previously reported in two unrelated families with resistance to thyroid hormone (RTH).
|
|
Academic Article
|
Resistance to thyrotropin (TSH) in three families is not associated with mutations in the TSH receptor or TSH.
|
|
Academic Article
|
Thyroxine-binding globulin: organization of the gene and variants.
|
|
Academic Article
|
Evaluation of pituitary and peripheral tissue markers of thyroid hormone action in an Iranian family with resistance to thyroid hormone.
|
|
Academic Article
|
Iodination-deiodination. A radiochemical method for detection of structure and changes in structure in RNA.
|
|
Academic Article
|
An additional carbohydrate chain in the variant thyroxine-binding globulin-Gary (TBGAsn-96) impairs its secretion.
|
|
Academic Article
|
Selective pituitary resistance to thyroid hormone produced by expression of a mutant thyroid hormone receptor beta gene in the pituitary gland of transgenic mice.
|
|
Academic Article
|
Modification of thyroid hormone and 9-cis retinoic acid signaling by overexpression of their cognate receptors using adenoviral vector.
|
|
Academic Article
|
Effect of thyroid hormone on growth. Lessons from the syndrome of resistance to thyroid hormone.
|
|
Academic Article
|
Dominant inheritance of resistance to thyroid hormone not linked to defects in the thyroid hormone receptor alpha or beta genes may be due to a defective cofactor.
|
|
Academic Article
|
Thyroid hormone action on liver, heart, and energy expenditure in thyroid hormone receptor beta-deficient mice.
|
|
Academic Article
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Familial dysalbuminemic hyperthyroxinemia in a Swiss family caused by a mutant albumin (R218P) shows an apparent discrepancy between serum concentration and affinity for thyroxine.
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Academic Article
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Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease.
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Academic Article
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Congenital central isolated hypothyroidism caused by a homozygous mutation in the TSH-beta subunit gene.
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Academic Article
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Autoantibodies from patients with autoimmune thyroid disease do not interfere with the activity of the human iodide symporter gene stably transfected in CHO cells.
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Academic Article
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Sequencing of the variant thyroxine-binding globulin (TBG)-San Diego reveals two nucleotide substitutions.
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Academic Article
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Mutations in the sodium/iodide symporter (NIS) gene as a cause for iodide transport defects and congenital hypothyroidism.
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Academic Article
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Identification of thyroxine-binding globulin-San Diego in a family from Houston and its characterization by in vitro expression using Xenopus oocytes.
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Academic Article
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Failure of membrane targeting causes the functional defect of two mutant sodium iodide symporters.
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Academic Article
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Five new families with resistance to thyroid hormone not caused by mutations in the thyroid hormone receptor beta gene.
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Academic Article
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Torpor in mice is induced by both leptin-dependent and -independent mechanisms.
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Academic Article
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Complete thyroxine-binding globulin (TBG) deficiency produced by a mutation in acceptor splice site causing frameshift and early termination of translation (TBG-Kankakee).
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Academic Article
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Aberrant alternative splicing of thyroid hormone receptor in a TSH-secreting pituitary tumor is a mechanism for hormone resistance.
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Academic Article
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Resistance to thyroid hormone does not abrogate the transient thyrotoxicosis associated with gestation: report of a case.
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Academic Article
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Resistance to thyroid hormone.
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Academic Article
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Congenital hypothyroidism in a child with unsuspected familial dysalbuminemic hyperthyroxinemia caused by a mutation (R218H) in the human albumin gene.
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Academic Article
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Recessive inheritance of thyroid hormone resistance caused by complete deletion of the protein-coding region of the thyroid hormone receptor-beta gene.
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Academic Article
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Complete thyroxine-binding globulin (TBG) deficiency in two families without mutations in coding or promoter regions of the TBG genes: in vitro demonstration of exon skipping.
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Academic Article
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Characterization of T(4)-binding globulin cleaved by human leukocyte elastase.
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Academic Article
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Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo.
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Academic Article
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Type 1 iodothyronine deiodinase in the house musk shrew (Suncus murinus, Insectivora: Soricidae): cloning and characterization of complementary DNA, unique tissue distribution and regulation by T(3).
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Academic Article
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Search for abnormalities of nuclear corepressors, coactivators, and a coregulator in families with resistance to thyroid hormone without mutations in thyroid hormone receptor beta or alpha genes.
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Academic Article
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Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone.
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Academic Article
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Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency.
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Academic Article
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Low TSH requirement and goiter in transgenic mice overexpressing IGF-I and IGF-Ir receptor in the thyroid gland.
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Academic Article
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Congenital secondary hypothyroidism caused by exon skipping due to a homozygous donor splice site mutation in the TSHbeta-subunit gene.
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Academic Article
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RXR receptor agonist suppression of thyroid function: central effects in the absence of thyroid hormone receptor.
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Academic Article
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The effect of short-term treatment with recombinant human thyroid-stimulating hormones on leydig cell function in men.
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Academic Article
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Reduced nuclear triiodothyronine receptors in starvation-induced hypothyroidism.
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Academic Article
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Resistance to thyroid hormone with and without receptor gene mutations.
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Academic Article
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Diverse abnormalities of the c-erbA beta thyroid hormone receptor gene in generalized thyroid hormone resistance.
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Academic Article
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Resistance to thyrotropin.
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Academic Article
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A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene.
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Academic Article
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Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice.
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Academic Article
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Hypothyroidism in thyroid transcription factor 1 haploinsufficiency is caused by reduced expression of the thyroid-stimulating hormone receptor.
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Academic Article
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Sequence of the variant thyroxine-binding globulin (TBG) in a Montreal family with partial TBG deficiency.
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Academic Article
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Sleep deprivation in the rat: XIII. The effect of hypothyroidism on sleep deprivation symptoms.
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Academic Article
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Partial thyroxine-binding globulin (TBG) deficiency in a family with no detectable mutation of the TBG gene.
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Academic Article
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Pseudomalabsorption of levothyroxine.
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Academic Article
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Regression of a large goiter in a patient with resistance to thyroid hormone by every other day treatment with triiodothyronine.
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Academic Article
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Genomic organization of mouse ZAKI-4 gene that encodes ZAKI-4 alpha and beta isoforms, endogenous calcineurin inhibitors, and changes in the expression of these isoforms by thyroid hormone in adult mouse brain and heart.
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Academic Article
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Partial deficiency of thyroxine-binding globulin-Allentown is due to a mutation in the signal peptide.
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Academic Article
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Analysis of the PAX8 gene in congenital hypothyroidism caused by different forms of thyroid dysgenesis in a father and daughter.
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Academic Article
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Congenital hypothyroidism due to a new deletion in the sodium/iodide symporter protein.
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Academic Article
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Three novel mutations causing complete T(4)-binding globulin deficiency.
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Academic Article
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Thyroid function and effect of aging in combined hetero/homozygous mice deficient in thyroid hormone receptors alpha and beta genes.
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Academic Article
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Characterization and primary structures of bovine and porcine thyroxine-binding globulin.
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Academic Article
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Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice.
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Academic Article
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Complete thyroxine-binding globulin (TBG) deficiency caused by a single nucleotide deletion in the TBG gene.
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Academic Article
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Fetal loss associated with excess thyroid hormone exposure.
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Academic Article
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A de novo mutation in an already mutant nucleotide of the thyroid hormone receptor beta gene perpetuates resistance to thyroid hormone.
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Academic Article
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The pathogenic role of anti-thyroglobulin antibody on pregnancy: evidence from an active immunization model in mice.
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Academic Article
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A new case of resistance to thyroid hormone caused by a de novo P453T mutation in the thyroid hormone receptor gene in an Israeli child.
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Academic Article
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Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo.
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Academic Article
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Autosomal dominant resistance to thyrotropin as a distinct entity in five multigenerational kindreds: clinical characterization and exclusion of candidate loci.
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Academic Article
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Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation.
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Academic Article
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Identification of a serum protein polymorphism via two-dimensional electrophoresis. Family and population studies in two genetically isolated groups: North American Hutterites and Australian aborigines.
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Academic Article
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Identification of a locus for nongoitrous congenital hypothyroidism on chromosome 15q25.3-26.1.
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Academic Article
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Mutations in SECISBP2 result in abnormal thyroid hormone metabolism.
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Academic Article
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Thyroid hormone mediated changes in gene expression can be initiated by cytosolic action of the thyroid hormone receptor beta through the phosphatidylinositol 3-kinase pathway.
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Academic Article
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Negative regulation by thyroid hormone receptor requires an intact coactivator-binding surface.
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Academic Article
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Nuclear receptors for thyroid hormone.
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Academic Article
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Unique regulation of thyroid hormone metabolism during fasting in the house musk shrew (Suncus murinus, Insectivora: Soricidae).
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Academic Article
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Neonatal detection of generalized resistance to thyroid hormone.
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Academic Article
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Sequencing of the variant thyroxine-binding globulin (TBG)-Quebec reveals two nucleotide substitutions.
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Academic Article
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Preferential megalin-mediated transcytosis of low-hormonogenic thyroglobulin: a control mechanism for thyroid hormone release.
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Academic Article
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Replacement of Leu227 by Pro in thyroxine-binding globulin (TBG) is associated with complete TBG deficiency in three of eight families with this inherited defect.
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Academic Article
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Defective thyroglobulin storage in LDL receptor-associated protein-deficient mice.
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Academic Article
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Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity.
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Academic Article
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Molecular basis for the properties of the thyroxine-binding globulin-slow variant in American blacks.
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Academic Article
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Abnormalities of triiodothyronine binding to lymphocyte and fibroblast nuclei from a patient with peripheral tissue resistance to thyroid hormone action.
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Academic Article
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The syndrome of resistance to thyroid stimulating hormone.
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Academic Article
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Clinical and genetic characteristics of congenital hypothyroidism due to mutations in the thyroid peroxidase (TPO) gene in Israelis.
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Academic Article
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International Union of Pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: thyroid hormone receptors.
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Academic Article
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Heterogeneous human prolactin from a giant pituitary tumor in a patient with panhypopituitarism.
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Academic Article
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Triiodothyronine stimulates specifically growth hormone mRNA in rat pituitary tumor cells.
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Academic Article
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Novel biological and clinical aspects of thyroid hormone metabolism.
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Academic Article
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Effects of maternal levels of thyroid hormone (TH) on the hypothalamus-pituitary-thyroid set point: studies in TH receptor beta knockout mice.
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Academic Article
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Syndromes of reduced sensitivity to thyroid hormone: genetic defects in hormone receptors, cell transporters and deiodination.
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Academic Article
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Familial juvenile autoimmune hypothyroidism, pituitary enlargement, obesity, and insulin resistance.
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Academic Article
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Sleep deprivation in the rat: XI. The effect of guanethidine-induced sympathetic blockade on the sleep deprivation syndrome.
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Academic Article
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Effect of total sleep deprivation on 5'-deiodinase activity of rat brown adipose tissue.
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Academic Article
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A novel splice variant involving the 5' untranslated region of thyroid hormone receptor beta1 (TRbeta1).
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Academic Article
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Comparison of primary and secondary stimulation of male rats by estradiol in terms of prolactin synthesis and mRNA accumulation in the pituitary.
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Academic Article
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Multiple endocrine neoplasia 2A syndrome presenting as peripartum cardiomyopathy due to catecholamine excess.
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Academic Article
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Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity.
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Academic Article
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Loss-of-function mutations in the thyrotropin receptor gene as a major determinant of hyperthyrotropinemia in a consanguineous community.
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Academic Article
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Thyroid hormone responsive genes in cultured human fibroblasts.
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Academic Article
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Importance of monocarboxylate transporter 8 for the blood-brain barrier-dependent availability of 3,5,3'-triiodo-L-thyronine.
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Academic Article
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X-linked paroxysmal dyskinesia and severe global retardation caused by defective MCT8 gene.
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Academic Article
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Tissue responses to thyroid hormone in a kindred with resistance to thyroid hormone harboring a commonly occurring mutation in the thyroid hormone receptor beta gene (P453T).
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Academic Article
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The syndrome of inherited partial SBP2 deficiency in humans.
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Academic Article
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Clinical and molecular characterization of a novel selenocysteine insertion sequence-binding protein 2 (SBP2) gene mutation (R128X).
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Academic Article
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Sleep deprivation in the rat: V. Energy use and mediation.
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Academic Article
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Sleep deprivation in the rat: IX. Recovery.
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Academic Article
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Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent.
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Academic Article
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A thyroid hormone analog with reduced dependence on the monocarboxylate transporter 8 for tissue transport.
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Academic Article
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A case of Resistance to Thyroid Hormone without mutation in the thyroid hormone receptor beta.
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Academic Article
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A new inherited abnormality of thyroxine-binding globulin (TBG-San Diego) with decreased affinity for thyroxine and triiodothyronine.
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Academic Article
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A mutation causing reduced biological activity and stability of thyroxine-binding globulin probably as a result of abnormal glycosylation of the molecule.
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Academic Article
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Generalized resistance to thyroid hormone associated with a mutation in the ligand-binding domain of the human thyroid hormone receptor beta.
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Academic Article
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Distinct and histone-specific modifications mediate positive versus negative transcriptional regulation of TSHalpha promoter.
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Academic Article
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Autoimmunity in patients with resistance to thyroid hormone.
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Academic Article
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Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor.
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Academic Article
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Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion.
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Academic Article
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Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice.
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Academic Article
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The syndrome of generalized resistance to thyroid hormone (GRTH).
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Academic Article
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Thyroid hormone receptor a and regulation of type 3 deiodinase.
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Academic Article
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Pendred syndrome in two Galician families: insights into clinical phenotypes through cellular, genetic, and molecular studies.
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Academic Article
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Selenium supplementation fails to correct the selenoprotein synthesis defect in subjects with SBP2 gene mutations.
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Academic Article
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Oncogenic Kras requires simultaneous PI3K signaling to induce ERK activation and transform thyroid epithelial cells in vivo.
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Academic Article
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Type 3 deiodinase deficiency results in functional abnormalities at multiple levels of the thyroid axis.
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Academic Article
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A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism.
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Academic Article
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Screening of nineteen unrelated families with generalized resistance to thyroid hormone for known point mutations in the thyroid hormone receptor beta gene and the detection of a new mutation.
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Academic Article
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Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors.
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Academic Article
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A single copy of the recently identified dual oxidase maturation factor (DUOXA) 1 gene produces only mild transient hypothyroidism in a patient with a novel biallelic DUOXA2 mutation and monoallelic DUOXA1 deletion.
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Academic Article
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Consecutive mutational events in a TSHR allele of Arab families with resistance to thyroid stimulating hormone.
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Academic Article
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Homozygous thyroid hormone receptor ß-gene mutations in resistance to thyroid hormone: three new cases and review of the literature.
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Academic Article
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Resistance to thyroid hormone: one of several defects causing reduced sensitivity to thyroid hormone.
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Academic Article
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Inherited thyroxine-binding globulin abnormalities in man.
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Academic Article
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Transsphenoidal surgery for Cushing disease: experience with 136 patients.
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Academic Article
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Disruption of the melanin-concentrating hormone receptor 1 (MCH1R) affects thyroid function.
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Academic Article
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Role of type 2 deiodinase in response to acute lung injury (ALI) in mice.
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Academic Article
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Two new inherited defects of the thyroxine-binding globulin (TBG) molecule presenting as partial TBG deficiency.
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Academic Article
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Graves' disease associated with familial deficiency of thyroxine-binding globulin.
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Academic Article
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Thyroid regeneration: characterization of clear cells after partial thyroidectomy.
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Academic Article
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Effect of estrogen on the synthesis and secretion of thyroxine-binding globulin by a human hepatoma cell line, Hep G2.
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Academic Article
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Normal cellular uptake of thyroxine from serum of patients with familial dysalbuminemic hyperthyroxinemia or elevated thyroxine-binding globulin.
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Academic Article
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Characterization of thyroxine-binding globulin secreted by a human hepatoma cell line.
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Academic Article
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Mutations in the NKX2.5 gene and the PAX8 promoter in a girl with thyroid dysgenesis.
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Academic Article
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Isoelectric focusing variant thyroxine-binding globulin in American blacks: increased heat lability and reduced serum concentration.
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Academic Article
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X-chromosome-linked inheritance of the variant thyroxine-binding globulin in Australian aborigines.
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Academic Article
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Hybridization of RNA labelled with 125 I to high specific activity.
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Academic Article
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The effects of low doses of depot estradiol and testosterone in teenagers with ovarian failure and Turner's syndrome.
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Academic Article
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The computer in the diagnosis of thyroid disease.
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Academic Article
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Studies of a sibship with apparent hereditary resistance to the intracellular action of thyroid hormone.
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Academic Article
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Elevated serum thyroglobulin level in congenital thyroxine-binding globulin deficiency.
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Academic Article
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Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes.
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Academic Article
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Resistance to thyroid hormone in a patient with thyroid dysgenesis.
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Academic Article
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Effects of "jet lag" on hormonal patterns. III. Demonstration of an intrinsic circadian rhythmicity in plasma prolactin.
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Academic Article
|
Resistance to thyroid hormone: an historical overview.
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Academic Article
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Human thyroxine-binding globulin gene: complete sequence and transcriptional regulation.
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Academic Article
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Identification of a functional polymorphism of the human type 5 17beta-hydroxysteroid dehydrogenase gene associated with polycystic ovary syndrome.
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Academic Article
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Variant thyroxine-binding globulin in serum of Australian aborigines: a comparison with familial TBG deficiency in Caucasians and American blacks.
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Academic Article
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Sequence of the variant thyroxine-binding globulin of Australian aborigines. Only one of two amino acid replacements is responsible for its altered properties.
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Academic Article
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Induction of hypothyroidism and hypoprolactinemia by growth hormone producing rat pituitary tumors.
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Academic Article
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Mice deficient in dual oxidase maturation factors are severely hypothyroid.
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Academic Article
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Dominant role of thyrotropin-releasing hormone in the hypothalamic-pituitary-thyroid axis.
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Academic Article
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Dominant negative transcriptional regulation by a mutant thyroid hormone receptor-beta in a family with generalized resistance to thyroid hormone.
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Academic Article
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A novel thyroid hormone receptor-beta mutation that fails to bind nuclear receptor corepressor in a patient as an apparent cause of severe, predominantly pituitary resistance to thyroid hormone.
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Academic Article
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Parameters of thyroid function in serum of 16 selected vertebrate species: a study of PBI, serum T4, free T4, and the pattern of T4 and T3 binding to serum proteins.
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Academic Article
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T3 thyrotoxicosis. Thyrotoxicosis due to elevated serum triiodothyronine levels.
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Academic Article
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The differential stimulatory effect of thyroid hormone on growth hormone synthesis and estrogen on prolactin synthesis due to accumulation of specific messenger ribonucleic acids.
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Academic Article
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Suppression of serum thyrotropin (TSH) by L-dopa in chronic hypothyroidism: interrelationships in the regulation of TSH and prolactin secretion.
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Academic Article
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Effects of 7, 12-dimethylbenz(a)anthracene and estrogen on the transplantation and growth of a rat pituitary tumor.
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Academic Article
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Genetic polymorphism of rhesus thyroxine-binding prealbumin: evidence for tetrameric structure in primates.
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Academic Article
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Serum tests for measurement of thyroid function.
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Academic Article
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The coexistence of a novel inactivating mutant thyrotropin receptor allele with two thyroid peroxidase mutations: a genotype-phenotype correlation.
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Academic Article
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Inherited defects of thyroid hormone metabolism.
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Academic Article
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Thyroid hormones and their receptors: from development to disease.
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Academic Article
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Inherited X chromosome linked thyroxine-binding globulin (TBG) deficiency in a homozygous female.
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Academic Article
|
Syndromes of thyroid hormone resistance.
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Academic Article
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Mosaicism of a thyroid hormone receptor-beta gene mutation in resistance to thyroid hormone.
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Academic Article
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Defective thyroid hormone feedback regulation in the syndrome of peripheral resistance to thyroid hormone.
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Academic Article
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The role of glycosylation in the molecular conformation and secretion of thyroxine-binding globulin.
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Academic Article
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The relationship between episodic variations of plasma prolactin and REM-non-REM cyclicity is an artifact.
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Academic Article
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Translation of thyroglobulin 33S messenger RNA as a means of determining thyroglobulin quaternary structure.
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Academic Article
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Cross-talk between PI3K and estrogen in the mouse thyroid predisposes to the development of follicular carcinomas with a higher incidence in females.
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Academic Article
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Radioautographic localization of prolactin messenger RNA on histological sections by in situ hybridization.
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Academic Article
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Quantitative analysis of spontaneous variations of plasma prolactin in normal man.
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Academic Article
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Molecular and structural characterization of the heat-resistant thyroxine-binding globulin-Chicago.
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Academic Article
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Radioimmunoassay for serum triiodothyronine: evaluation of simple techniques to control interference from binding proteins.
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Academic Article
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Continuing occurrence of thyroid carcinoma after irradiation to the neck in infancy and childhood.
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Academic Article
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Stanniocalcin 1 induction by thyroid hormone depends on thyroid hormone receptor ß and phosphatidylinositol 3-kinase activation.
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Academic Article
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Nuclear triiodothyronine-binding protein: partial characterization and binding to chromatin.
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Academic Article
|
The preparation of carrier-free iodine isotope-substituted cytosine nucleotides.
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Academic Article
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Alterations in thyroxine (T 4 ) and tri-iodothyronine (T 3 ) binding to serum proteins by heat.
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Academic Article
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Gene screening in Japanese families with complete deficiency of thyroxine-binding globulin demonstrates that a nucleotide deletion at codon 352 may be a race specific mutation.
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Academic Article
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Relationship of oligosaccharide modification to the cause of serum thyroxine-binding globulin excess.
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Academic Article
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Disappearance rate of endogenous and exogenous human growth hormone in man.
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Academic Article
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Serum albumin and antibodies in the diagnosis of thyroid cancer.
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Academic Article
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Direct application of radioiodinated aminoacyl tRNA for radiolabeling nascent proteins.
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Academic Article
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Measurement of thyroxine uptake from serum by cultured human hepatocytes as an index of thyroid status: reduced thyroxine uptake from serum of patients with nonthyroidal illness.
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Academic Article
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Resistance to thyroid hormone diagnosed by the reduced response of fibroblasts to the triiodothyronine-induced suppression of fibronectin synthesis.
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Academic Article
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Rapid control of thyrotoxicosis with combined 131I, anthithyroid drugs and KI therapy.
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Academic Article
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Genetic polymorphism in rhesus C3 and Gc globulin.
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Academic Article
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Chiari-Frommel syndrome in a patient with primary adrenocortical insufficiency.
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Academic Article
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Estimation of the T 4 binding capacity of serum TBG and TBPA by a single T 4 load ion exchange resin method.
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Academic Article
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Effects of "jet lag" on hormonal patterns. I. Procedures, variations in total plasma proteins, and disruption of adrenocorticotropin-cortisol periodicity.
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Academic Article
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Endemic goiter with hypothyroidism in three generations.
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Academic Article
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Familial syndrome combining deaf-mutism, stuppled epiphyses, goiter and abnormally high PBI: possible target organ refractoriness to thyroid hormone.
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Academic Article
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Familial thyroxine-binding globulin deficiency in a patient with Turner's syndrome (XO). Genetic study of a kindred.
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Academic Article
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Peroxidase defect in congenital goiter with complete organification block.
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Academic Article
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TBG deficiency: description of two novel mutations associated with complete TBG deficiency and review of the literature.
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Academic Article
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Loss of bioreactivity and preservation of immunoreactivity of iodothyrotropin-releasing hormone.
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Academic Article
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Thyroid function in a uremic rat model. Evidence suggesting tissue hypothyroidism.
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Academic Article
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Bidirectional thyroxine exchange in pregnant sheep.
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Academic Article
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Early in vitro induction of rat pituitary GH mRNA by T31.
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Academic Article
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Metabolism of L-thyroxine (T4) and L-triiodothyronine (T3) by human fibroblasts in tissue culture: evidence for cellular binding proteins and conversion of T4 to T3.
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Academic Article
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Measurement of circulating thyroid microsomal antibodies by the tanned red cell haemagglutination technique: its usefulness in the diagnosis of autoimmune thyroid diseases.
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Academic Article
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Regulation of glycosaminoglycan synthesis by thyroid hormone in vitro.
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Academic Article
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Effects of "jet lag" on hormonal patterns. II. Adaptation of melatonin circadian periodicity.
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Academic Article
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Modulation of thyroglobulin messenger RNA accumulation in the rat thyroid.
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Academic Article
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High prevalence of thyroxine-binding globulin deficiency among Bedouin infants in southern Israel.
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Academic Article
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The value of serum thyroglobulin measurement in clinical practice.
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Academic Article
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Hormonal regulation of glycosaminoglycan accumulation in fibroblasts from patients with resistance to thyroid hormone.
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Academic Article
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Thyroid dysfunction in chronic renal failure. A study of the pituitary-thyroid axis and peripheral turnover kinetics of thyroxine and triiodothyronine.
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Academic Article
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Expression of a thyroid hormone-responsive recombinant gene introduced into adult mice livers by replication-defective adenovirus can be regulated by endogenous thyroid hormone receptor.
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Academic Article
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Isolation of rat prolactin messenger ribonucleic acid and synthesis of the complementary deoxyribonucleic acid.
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Academic Article
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How clinical observations of a congenital disease can be translated in terms of molecular biology.
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Academic Article
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Transient iodide trapping defect in Hashimoto's thyroiditis detected by the combination of radionuclide and fluorescent scanning.
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Academic Article
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Diurnal rhythm in total serum thyroxine levels.
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Academic Article
|
Common tests of thyroid function in serum.
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Academic Article
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Pituitary-thyroid setpoint and thyrotropin receptor expression in consomic rats.
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Academic Article
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Carcinoembryonic antigen and humoral antibody response in patients with thyroid carcinoma.
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Academic Article
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Radioiodine labeling of ribopolymers for special applications in biology.
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Academic Article
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Sleep deprivation in the rat: XIX. Effects of thyroxine administration.
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Academic Article
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Pretibial myxedema--a reversible cause of foot drop due to entrapment of the peroneal nerve.
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Academic Article
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Nocturnal exercise phase delays circadian rhythms of melatonin and thyrotropin secretion in normal men.
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Academic Article
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Molecular basis of inherited thyroxine-binding globulin defects.
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Academic Article
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Thyroid hormone relationships between maternal and fetal circulations in human pregnancy at term: a study in patients with normal and abnormal thyroid function.
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Academic Article
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Congenital neonatal hyperthyroidism caused by germline mutations in the TSH receptor gene.
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Academic Article
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Familial goitre with partial iodine organification defect, lack of thyroglobulin, and high levels of thyroid peroxidase.
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Academic Article
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Radioimmunoassays specific for the tertiary and primary structures of thyroxine-binding globulin (TBG): measurement of denatured TBG in serum.
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Academic Article
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The influence of percutaneous fine needle aspiration on serum thyroglobulin.
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Academic Article
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Simultaneous translation of growth hormone and prolactin messenger RNA from rat pituitary tumor cells.
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Academic Article
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Postirradiation screening for thyroid nodules.
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Academic Article
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Linkage of familial dysalbuminemic hyperthyroxinemia to the albumin gene in a large Amish kindred.
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Academic Article
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Demonstration of rapid light-induced advances and delays of the human circadian clock using hormonal phase markers.
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Academic Article
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An identical missense mutation in the albumin gene results in familial dysalbuminemic hyperthyroxinemia in 8 unrelated families.
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Academic Article
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A somatic gain-of-function mutation in the thyrotropin receptor gene producing a toxic adenoma in an infant.
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Academic Article
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In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice.
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Academic Article
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Comparison of thyroidectomized calf serum and stripped serum for the study of thyroid hormone action in human skin fibroblasts in vitro.
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Academic Article
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White matter abnormalities and dystonic motor disorder associated with mutations in the SLC16A2 gene.
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Academic Article
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Approach to the patient with resistance to thyroid hormone and pregnancy.
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Academic Article
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Functional characteristics of a variant thyrotropin receptor.
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Academic Article
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Distinct roles of deiodinases on the phenotype of Mct8 defect: a comparison of eight different mouse genotypes.
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Academic Article
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Translation of prolactin and growth hormone messenger RNA from rat pituitary tumour cells. Stimulation of GH mRNA activity by triiodothyronine [proceedings].
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Academic Article
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The effect of dexamethasone on the 24-hour profiles of adrenocorticotropin and cortisol in Cushing's syndrome.
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Academic Article
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Multifactorial control of the 24-hour secretory profiles of pituitary hormones.
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Academic Article
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Inherited abnormality of thyroxine-binding globulin with no demonstrable thyroxine-binding activity and high serum levels of denatured thyroxine-binding globulin.
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Academic Article
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Evidence for two subtypes of Cushing's disease based on the analysis of episodic cortisol secretion.
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Academic Article
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Variant thyroxine-binding globulin in serum of Australian aborigines: its physical, chemical and biological properties.
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Academic Article
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The radioiodination of ribopolymers for use in hybridizational and molecular analyses.
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Academic Article
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Diagnosis and management of thyroid diseases in pregnancy.
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Academic Article
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Thyrotropin controls transcription of the thyroglobulin gene.
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Academic Article
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Effects of "jet lag" on hormonal patterns. IV. Time shifts increase growth hormone release.
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Academic Article
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The effect of thyroid hormone on glycosaminoglycan accumulation in human skin fibroblasts.
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Academic Article
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Dopaminergic control of prolactin mRNA accumulation in the pituitary of the male rat.
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Academic Article
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Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase.
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Academic Article
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Hypothyroidism in a Brazilian kindred due to iodide trapping defect caused by a homozygous mutation in the sodium/iodide symporter gene.
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Academic Article
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Resistance to thyroid hormone in subjects from two unrelated families is associated with a point mutation in the thyroid hormone receptor beta gene resulting in the replacement of the normal proline 453 with serine.
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Academic Article
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Congenital hypothyroidism due to mutations in the sodium/iodide symporter. Identification of a nonsense mutation producing a downstream cryptic 3' splice site.
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Academic Article
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Complete deficiency of thyroxine-binding globulin (TBG-CD Buffalo) caused by a new nonsense mutation in the thyroxine-binding globulin gene.
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Academic Article
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Familial dysalbuminemic hypertriiodothyroninemia: a new, dominantly inherited albumin defect.
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Academic Article
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A novel point mutation in cluster 3 of the thyroid hormone receptor beta gene (P247L) causing mild resistance to thyroid hormone.
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Academic Article
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Increased sensitivity to thyroid hormone in mice with complete deficiency of thyroid hormone receptor alpha.
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Academic Article
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Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus.
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Academic Article
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Molecular cloning and primary structure of rat thyroxine-binding globulin.
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Academic Article
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Four new cases of congenital secondary hypothyroidism due to a splice site mutation in the thyrotropin-beta gene: phenotypic variability and founder effect.
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Academic Article
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Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts.
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Academic Article
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Resistance to thyroid hormone.
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Academic Article
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Differentiation of two abnormalities in thyroid peroxidase causing organification defect and goitrous hypothyroidism.
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Academic Article
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Resistance to thyroid hormone associated with autoimmune thyroid disease in a Turkish family.
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Academic Article
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Repulsive separation of the cytoplasmic ends of transmembrane helices 3 and 6 is linked to receptor activation in a novel thyrotropin receptor mutant (M626I).
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Academic Article
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Serum thyrotropin and prolactin in the syndrome of generalized resistance to thyroid hormone: responses to thyrotropin-releasing hormone stimulation and short term triiodothyronine suppression.
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Academic Article
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Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice.
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Academic Article
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A familial thyrotropin (TSH) receptor mutation provides in vivo evidence that the inositol phosphates/Ca2+ cascade mediates TSH action on thyroid hormone synthesis.
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Academic Article
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Biallelic inactivation of the dual oxidase maturation factor 2 (DUOXA2) gene as a novel cause of congenital hypothyroidism.
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Academic Article
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A novel monocarboxylate transporter 8 gene mutation as a cause of severe neonatal hypotonia and developmental delay.
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Academic Article
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Thyroid hormone receptor beta gene mutation (P453A) in a family producing resistance to thyroid hormone.
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Academic Article
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Metabolism of thyroxine-binding globulin in man. Abnormal rate of synthesis in inherited thyroxine-binding globulin deficiency and excess.
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Academic Article
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The action of thyroid hormone.
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Academic Article
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Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice.
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Academic Article
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Genetic causes of congenital hypothyroidism due to dyshormonogenesis.
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Academic Article
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Leukocyte alkaline phosphatase in hypothyroidism and hyperthyroidism. Response to initiation of thyroxine replacement therapy.
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Academic Article
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Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation.
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Academic Article
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Detection of the thyroxine-binding globulin (TBG) gene in six unrelated families with complete TBG deficiency.
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Academic Article
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Generation of functional thyroid from embryonic stem cells.
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Academic Article
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Inherited heat-stable variant thyroxine-binding globulin (TBG-Chicago).
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Academic Article
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Reduced affinity for thyroxine in two of three structural thyroxine-binding prealbumin variants associated with familial amyloidotic polyneuropathy.
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Academic Article
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Reduced clearance rate of thyroxine-binding globulin (TBG) with increased sialylation: a mechanism for estrogen-induced elevation of serum TBG concentration.
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Academic Article
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A study on the inheritance of thyroxine-binding globulin (TBG) deficiency from data obtained in 13 families detected by a neonatal screening program.
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Academic Article
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Study of four new kindreds with inherited thyroxine-binding globulin abnormalities. Possible mutations of a single gene locus.
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Academic Article
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Neonatal hypothyroidism and goiter in one infant of each of two sets of twins due to maternal therapy with antithyroid drugs.
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Academic Article
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Abnormal thyroxine metabolism in hyposomatotrophic dwarfism and inhibition of responsiveness to TRH during GH therapy.
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Academic Article
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Parameters of thyroid function in maternal and cord serum at term pregnancy.
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Academic Article
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Studies on human thyroxine-binding globulin (TBG). IX. Some physical, chemical, and biological properties of radioiodinated TBG and partially desialylated TBG.
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Academic Article
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Reduced triiodothyronine content in liver but not pituitary of the uremic rat model: demonstration of changes compatible with thyroid hormone deficiency in liver only.
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Academic Article
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Thyroid hormone therapy.
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Academic Article
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Growth hormone responses to thyroid hormone in the neonatal rat: resistance and anamnestic response.
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Academic Article
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Do clinical manifestations of resistance to thyroid hormone correlate with the functional alteration of the corresponding mutant thyroid hormone-beta receptors?
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Academic Article
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Studies on the repression of basal transcription (silencing) by artificial and natural human thyroid hormone receptor-beta mutants.
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Academic Article
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Nomenclature of thyroid hormone receptor beta gene mutations in resistance to thyroid hormone. First workshop on thyroid hormone resistance, July 10-11, 1993, Cambridge, U.K.
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Academic Article
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Diiodothyropropionic acid (DITPA) in the treatment of MCT8 deficiency.
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Academic Article
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The syndromes of reduced sensitivity to thyroid hormone.
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Academic Article
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A clinically euthyroid child with a large goiter due to a thyroglobulin gene defect: clinical features and genetic studies.
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Academic Article
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Coexistence of THRB and TBG gene mutations in a Turkish family.
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Academic Article
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Management of differentiated thyroid cancer in the presence of resistance to thyroid hormone and TSH-secreting adenomas: a report of four cases and review of the literature.
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Academic Article
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Two cases of thyroid dysgenesis caused by different novel PAX8 mutations in the DNA-binding region: in vitro studies reveal different pathogenic mechanisms.
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Academic Article
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Changes in thyroid status during perinatal development of MCT8-deficient male mice.
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Academic Article
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A novel mechanism of inherited TBG deficiency: mutation in a liver-specific enhancer.
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Academic Article
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Tissue-specific posttranslational modification allows functional targeting of thyrotropin.
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Academic Article
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Placenta passage of the thyroid hormone analog DITPA to male wild-type and Mct8-deficient mice.
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Academic Article
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Familial dysalbuminemic hyperthyroxinemia in a 4-year-old girl with hyperactivity, palpitations and advanced dental age: how gold standard assays may be misleading.
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Academic Article
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Mutations of the thyroid hormone transporter MCT8 cause prenatal brain damage and persistent hypomyelination.
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Academic Article
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Incidental identification of a thyroid hormone receptor beta (THRB) gene variant in a family with autoimmune thyroid disease.
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Academic Article
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Long-term outcome of loss-of-function mutations in thyrotropin receptor gene.
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Academic Article
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American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models.
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Academic Article
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Inherited defects of thyroid hormone-cell-membrane transport: review of recent findings.
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Academic Article
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Mct8-deficient mice have increased energy expenditure and reduced fat mass that is abrogated by normalization of serum T3 levels.
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Academic Article
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Increased oxidative metabolism and neurotransmitter cycling in the brain of mice lacking the thyroid hormone transporter SLC16A2 (MCT8).
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Academic Article
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A new family with an activating mutation (G431S) in the TSH receptor gene: a phenotype discussion and review of the literature.
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Academic Article
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A novel mutation in the Albumin gene (R218S) causing familial dysalbuminemic hyperthyroxinemia in a family of Bangladeshi extraction.
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Academic Article
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Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.
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Academic Article
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Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.
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Academic Article
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Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.
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Academic Article
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Obatoclax overcomes resistance to cell death in aggressive thyroid carcinomas by countering Bcl2a1 and Mcl1 overexpression.
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Academic Article
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A mouse model suggests two mechanisms for thyroid alterations in infantile cystinosis: decreased thyroglobulin synthesis due to endoplasmic reticulum stress/unfolded protein response and impaired lysosomal processing.
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Academic Article
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A TSHß Variant with Impaired Immunoreactivity but Intact Biological Activity and Its Clinical Implications.
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Academic Article
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The Thyroid Hormone Analog DITPA Ameliorates Metabolic Parameters of Male Mice With Mct8 Deficiency.
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Academic Article
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Inherited defects of thyroxine-binding proteins.
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Academic Article
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Diiodothyropropionic acid (DITPA) cross-reacts with thyroid function assays on different immunoassay platforms.
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Academic Article
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Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model.
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Academic Article
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Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult Mice.
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Academic Article
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Aberrant Cerebellar Development in Mice Lacking Dual Oxidase Maturation Factors.
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Academic Article
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Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.
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Academic Article
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Adeno Associated Virus 9-Based Gene Therapy Delivers a Functional Monocarboxylate Transporter 8, Improving Thyroid Hormone Availability to the Brain of Mct8-Deficient Mice.
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Academic Article
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A Novel Thyroid Hormone Receptor Beta Gene Mutation (G251V) in a Thai Patient with Resistance to Thyroid Hormone Coexisting with Pituitary Incidentaloma.
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Academic Article
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Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin.
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Academic Article
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A Novel Mutation (S54C) of the PAX8 Gene in a Family with Congenital Hypothyroidism and a High Proportion of Affected Individuals.
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Academic Article
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DUOX2 Gene Mutation Manifesting as Resistance to Thyrotropin Phenotype.
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Academic Article
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Diagnostic Dilemma in Discordant Thyroid Function Tests Due to Thyroid Hormone Autoantibodies.
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Academic Article
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Thyroid Hormone Action on Liver, Heart, and Energy Expenditure in Thyroid Hormone Receptor ß-Deficient Mice* * Presented in part at the 69th Annual Meeting of the American Thyroid Association Meeting, November 14-17, 1996, San Diego, California. This study was supported in part by the National Institutes of Health Grant DK-17050 and the Seymour J. Abrams Thyroid Research Center; a grant from the Ministry of Health and Welfare, Japan (to H.S.); and Grant-in-Aid for Scientific Research (0967104...
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Academic Article
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A new TRß mutation in resistance to thyroid hormone syndrome.
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Academic Article
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Steroid Receptor Coactivator-1 Deficiency Causes Variable Alterations in the Modulation of T3-Regulated Transcription of Genes in Vivo.
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Academic Article
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TRH Action Is Impaired in Pituitaries of Male IGSF1-Deficient Mice.
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Academic Article
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Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier.
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Academic Article
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Changes in Hepatic TRß Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model.
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Academic Article
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Fetal Exposure to High Maternal Thyroid Hormone Levels Causes Central Resistance to Thyroid Hormone in Adult Humans and Mice.
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Academic Article
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An Essential Physiological Role for MCT8 in Bone in Male Mice.
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Academic Article
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Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia.
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Academic Article
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Resistance to thyrotropin.
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Academic Article
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Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families.
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Academic Article
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13th International Workshop on Resistance to Thyroid Hormone and Thyroid Hormone Action.
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Academic Article
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Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature.
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Academic Article
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A Novel Mutation in the TBG Gene Producing Partial Thyroxine-Binding Globulin Deficiency (Glencoe) Identified in 2 Families.
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Academic Article
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Novel Mutations in the NKX2.1 gene and the PAX8 gene in a Boy with Brain-Lung-Thyroid Syndrome.
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Academic Article
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Human Genetics of Thyroid Hormone Receptor Beta: Resistance to Thyroid Hormone Beta (RTHß).
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Academic Article
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A novel mutation in the TG gene (G2322S) causing congenital hypothyroidism in a Sudanese family: a case report.
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Academic Article
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Homozygous Mutation in Human Serum Albumin and Its Implication on Thyroid Tests.
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Academic Article
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Prenatal Diagnosis of Resistance to Thyroid Hormone and Its Clinical Implications.
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Academic Article
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Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism.
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Academic Article
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Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo.
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Academic Article
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GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation.
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Academic Article
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NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland.
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Academic Article
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Reduced Sensitivity to Thyroid Hormone as a Transgenerational Epigenetic Marker Transmitted Along the Human Male Line.
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Academic Article
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A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia.
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Academic Article
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Clinical recognition and evaluation of patients with inherited serum thyroid hormone-binding protein mutations.
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Academic Article
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Interconnection between circadian clocks and thyroid function.
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Academic Article
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Very Severe Resistance to Thyroid Hormone ß in One of Three Affected Members of a Family with a Novel Mutation in the THRB Gene.
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Academic Article
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Increased Anaplastic Lymphoma Kinase Activity Induces a Poorly Differentiated Thyroid Carcinoma in Mice.
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Academic Article
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Class III PI3K Vps34 Controls Thyroid Hormone Production by Regulating Thyroglobulin Iodination, Lysosomal Proteolysis, and Tissue Homeostasis.
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Academic Article
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Intracerebroventricular administration of the thyroid hormone analog TRIAC increases its brain content in the absence of MCT8.
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Academic Article
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Free Thyroxine Concentrations in Sera of Individuals with Familial Dysalbuminemic Hyperthyroxinemia: A Comparison of Three Methods of Measurement.
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Academic Article
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Sorting Variants of Unknown Significance Identified by Whole Exome Sequencing: Genetic and Laboratory Investigations of Two Novel MCT8 Variants.
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Academic Article
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Insertion of an Alu Element in Thyroglobulin Gene as a Novel Cause of Congenital Hypothyroidism.
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Academic Article
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Increased Prevalence of TG and TPO Mutations in Sudanese Children With Congenital Hypothyroidism.
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Academic Article
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Nonautoimmune Hyperthyroidism Caused by a Somatic Mosaic GNAS Mutation Involving Part of the Thyroid Gland.
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Academic Article
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Central Congenital Hypothyroidism Caused by a Novel Mutation, C47W, in the Cysteine Knot Region of TSHß.
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Academic Article
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A Novel G385E Variant in the Cold Region of the T3-Binding Domain of Thyroid Hormone Receptor Beta Gene and Investigations to Assess Its Clinical Significance.
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Academic Article
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Re: "Goiter in Residents of Salta, Argentina: An Artistic Rendition" by Jonklaas et al. (Thyroid 2020:30;34-36. DOI: 10.1089/thy.2019.0639).
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Academic Article
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Intranasal delivery of Thyroid hormones in MCT8 deficiency.
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Academic Article
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Mice Hypomorphic for Keap1, a Negative Regulator of the Nrf2 Antioxidant Response, Show Age-Dependent Diffuse Goiter with Elevated Thyrotropin Levels.
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Academic Article
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Human Type 1 Iodothyronine Deiodinase (DIO1) Mutations Cause Abnormal Thyroid Hormone Metabolism.
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Academic Article
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Prenatal Treatment of Thyroid Hormone Cell Membrane Transport Defect Caused by MCT8 Gene Mutation.
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Academic Article
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Early Diagnosis and Treatment of an Infant with a Novel Thyroid Hormone Receptor a Gene (pC380SfsX9) Mutation.
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Academic Article
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SWI/SNF Complex Mutations Promote Thyroid Tumor Progression and Insensitivity to Redifferentiation Therapies.
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Academic Article
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Increased Hepatic Fat Content in Patients with Resistance to Thyroid Hormone Beta.
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Academic Article
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Resistance to Thyroid Hormone Beta: A Focused Review.
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Academic Article
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Measurement of Reverse Triiodothyronine Level and the Triiodothyronine to Reverse Triiodothyronine Ratio in Dried Blood Spot Samples at Birth May Facilitate Early Detection of Monocarboxylate Transporter 8 Deficiency.
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Academic Article
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Novel DIO1 Gene Mutation Acting as Phenotype Modifier for Novel Compound Heterozygous TPO Gene Mutations Causing Congenital Hypothyroidism.
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Academic Article
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XB130 Deficiency Causes Congenital Hypothyroidism in Mice due to Disorganized Apical Membrane Structure and Function of Thyrocytes.
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Academic Article
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Triiodothyroacetic Acid Cross-Reacts With Measurement of Triiodothyronine (T3) on Various Immunoassay Platforms.
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Academic Article
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XB130 Plays an Essential Role in Folliculogenesis Through Mediating Interactions Between Microfilament and Microtubule Systems in Thyrocytes.
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Academic Article
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Pathogenesis of Multinodular Goiter in Elderly XB130-Deficient Mice: Alteration of Thyroperoxidase Affinity with Iodide and Hydrogen Peroxide.
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Academic Article
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TSHB R75G is a founder variant and prevalent cause of low or undetectable TSH in Indian Jews.
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Academic Article
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Severe Resistance to Thyroid Hormone Beta in a Patient with Athyreosis.
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Academic Article
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Thyroidal Transcriptomic Profiles of Pathoadaptive Responses to Congenital Hypothyroidism in XB130 Knockout Mice.
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Academic Article
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AAV9-MCT8 Delivery at Juvenile Stage Ameliorates Neurological and Behavioral Deficits in a Mouse Model of MCT8-Deficiency.
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Academic Article
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A Novel Pathogenic Variant in PAX8 Leads to Familial Congenital Hypothyroidism.
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Academic Article
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Maintaining the thyroid gland in mutant thyroglobulin-induced hypothyroidism requires thyroid cell proliferation that must continue in adulthood.
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Academic Article
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Congenital Hypothyroidism in Two Sudanese Families Harboring a Novel Iodotyrosine Deiodinase Mutation (IYD R279C).
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Academic Article
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Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism.
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Academic Article
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Foxe1 Deletion in the Adult Mouse Is Associated With Increased Thyroidal Mast Cells and Hypothyroidism.
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Academic Article
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Iodotyrosines Are Biomarkers for Preclinical Stages of Iodine-Deficient Hypothyroidism in Dehal1-Knockout Mice.
|
|
Concept
|
Cellular Reprogramming Techniques
|
|
Concept
|
Kelch-Like ECH-Associated Protein 1
|
|
Concept
|
PAX8 Transcription Factor
|
|
Concept
|
Protein Domains
|
|
Concept
|
Homeobox Protein Nkx-2.5
|
|
Concept
|
Thyroid Nuclear Factor 1
|
|
Concept
|
Dual Oxidases
|
|
Concept
|
Hyaluronan Synthases
|
|
Concept
|
Mechanistic Target of Rapamycin Complex 1
|
|
Concept
|
Acid Sensing Ion Channels
|
|
Concept
|
Myeloid Cell Leukemia Sequence 1 Protein
|
|
Concept
|
Calcineurin Inhibitors
|
|
Concept
|
Absorption, Physiological
|
|
Concept
|
Thyroid Carcinoma, Anaplastic
|
|
Grant
|
3RD INTERNATL WORKSHOP ON RESISTANCE TO THYROID HORMONE
|
|
Grant
|
THYROID PHYSIOLOGY STUDIES OF INHERITED DISORDERS
|
|
Grant
|
Thyroid Physiology Studies of Inherited Disorders
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Academic Article
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Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut.
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Academic Article
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Effect of the Fetal THRB Genotype on the Placenta.
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Academic Article
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Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland.
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Academic Article
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Increased cardiovascular morbidity and mortality in patients with resistance to thyroid hormone.
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Academic Article
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ASIC1a affects hypothalamic signaling and regulates the daily rhythm of body temperature in mice.
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Academic Article
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The Relationship Between Fetal THRB Genotype and Maternal Thyroid Function.
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Academic Article
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Impaired T3 uptake and action in MCT8-deficient cerebral organoids underlie Allan-Herndon-Dudley syndrome.
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